A thief escaping from the police and the stolen car hears a baby crying in the backseat. A woman applying for her dream job is fired from her current position, which she needs to keep her home. A baseball player who has to get a hit to win the game finds out his estranged son is in the stands.
One more point–all mistakes must be clear to the reader. It is good to do what Dorothy did and make them explicit. This is not a place to get artful.
Stakes and rising stakes provide one of the most effective ways to keep readers turning the pages. Get them to fret. Get them to worry. Make it excruciating. They'll love you for it.